Multivariate analysis indicated that the location of the primary tumor [hazard ratio (HR) = 0.3210, 95% CI = 0.164–0.627, p = 0.001], pathological differentiation (HR = 0.5014, 95% CI = 0.258–0.973, p = 0.041), pretreatment CEA (HR = 3.1573, 95% CI = 1.574–6.332, p = 0.001), and pretreatment CAR (HR = 3.9310, 95% CI = 2.116–7.303, p < 0.001) were independent prognostic factors for OS. Here, CEACAM5 is linked to neoplasm.