SOX2 and cancer: The stem cell signaling molecules (Notch related) were overexpressed in cervical cancer adherent cells as a result of 1 Gy C-ion (Figure 1), but there was no change in the expression level of these molecules along with other cancer stem cell markers (Nanog, SOX2 and OCT4A) in the spheroid populations (Figures 5B, C and Supplementary Figure S5).