The canonical pathway analysis by IPA of these FASN inhibitory transcriptomes identified a conserved upregulation of immune signaling (tumor necrosis factor, interferon, CD27, CD28, IL1, IL6, IL9, and BCR signaling), apoptosis signaling, cAMP, protein kinase A, and NRF-2-mediated oxidative stress response pathways as activated mechanisms by FASN inhibition in NHL cells (Figure 1C). Here, TNF is linked to non-Hodgkin lymphoma.