ALB and craniopharyngioma: This result was supported by Karnezis et al. Their research examined 1,108 people with pituitary adenomas and 53 people with craniopharyngiomas who underwent endoscopic sellar surgery, and mild liver disease was revealed to be a risk factor for iCSF leakage (OR=3.636, p =0.046), which usually lead to low albumin levels.