Several studies have shown that extracts or constituents of Zizyphi Semen, a component herb of KIT, ameliorates cognitive and memory impairment and reduced hippocampal neurogenesis in several animal models.27, 28, 29, 30, 31 These component herbs in KIT may act synergistically with Polygalae Radix. The gene discussed is KIT; the disease is memory impairment.