CXCL10 and tropical spastic paraparesis: However, the sole increased relative levels of inflammatory chemokines CXCL10 and CCL2 in the CSF of HTLV-1 AC did not result in pleocytosis or elevation of other biomarkers of neuroinflammation, as observed in non-infected individuals, suggesting that a combination of multiple events more likely triggers the development of HAM/TSP.