Since the PLZF moiety of PLZF-ABL1 and the IKZF1 moiety of IKZF1-Notch1 carry a structural degron for CRL4CRBN, we speculate that pomalidomide and lenalidomide may also be effective for the treatment of T-ALL carrying these fusion proteins. Here, ABL1 is linked to acute lymphoblastic leukemia.