Patients in the other MNDs group had significantly higher CSF NFL and CSF pNFH levels than patients with neuropathies & myelopathies (p < 0.05 for both), myopathies (p < 0.01 for both) and controls with no neurological disorder (p < 0.01 for both) (Fig. 2A,C). Here, NEFL is linked to nervous system disorder.