NEFL and amyotrophic lateral sclerosis: ALS patients had significantly higher CSF NFL and CSF pNFH levels than patients with neuropathies & myelopathies (p < 0.01 for both), patients with myopathies (p < 0.01 for both) and controls with no neurological disorder (p < 0.01 for both) (Fig. 2A,C).