CRP and malaria: Subgroup analysis of continents demonstrated a higher mean CRP level in patients with uncomplicated malaria than in febrile/healthy controls in studies conducted in Africa (p < 0.001, SMD: 3.26, 95% CI: 1.52–5.01, I2: 96.5%, four studies) and Asia (p < 0.001, SMD: 3.38, 95% CI: 3.01–3.75, I2: 0%, two studies).