A meta-analysis of the difference in mean CRP level between patients with uncomplicated malaria and febrile/healthy controls were divided into three subgroups: uncomplicated malaria and febrile controls, uncomplicated malaria and healthy controls, and uncomplicated malaria and febrile/healthy controls because previous studies27,46 reported the mean/median CRP levels of febrile and healthy controls. The gene discussed is CRP; the disease is malaria.