Thus, the enhanced intratumor production of pro-apoptotic Bax protein and the strong reduction of intratumor production of IL-6 and Fas-L (Figs. 3A, 4A, B and Table 3), which are of critical importance for cancer cell survival, demonstrate the sensitivity of tumor cells to the combined liposomal therapy and indicate induction of apoptosis9,13,31,50. This evidence concerns the gene BAX and neoplasm.