Associate genes are mainly involved in pathways such as: EGFR tyrosine kinase inhibitor resistance, ErbB signaling pathway, Ras signaling pathway, Colorectal cancer, Non-small cell lung cancer, Glioma, Renal cell carcinoma, Pancreatic cancer, Phospholipase D signaling pathway and Chronic myeloid leukemia. The gene discussed is EGFR; the disease is central nervous system cancer.