BRCA2 and neoplasm: Previous reports have shown that both BRCA1 and 2 tumors tend to be BL1 and BL2 TNBCtypes, BRCA1 tumors tend to be basal-like PAM50 subtype with high tumor inflammation signatures and many tumor-infiltrating immune cells, and BRCA2 tumors tend to be luminal A/B PAM50 subtype20–25.