Like in neutrophils, SLE-IgG induced CREMα nuclear translocation also in T cells, which resulted in increased CREMα binding to the IL-2 promotor and suppression of IL2 gene transcription.4 Interestingly, SLE-IgG induced GPX4 suppression as well as lower viability was restricted to SLE neutrophils and not present in T lymphocytes. Here, IL2 is linked to systemic lupus erythematosus.