Severity of the disease is graded according to Maddrey’s discriminant function (mDF) (based on bilirubin and prothrombin time), Glasgow alcoholic hepatitis score (based on age, white blood cell count, urea, prothrombin time and bilirubin) or Model for End-Stage Liver Disease (MELD) score (based on creatinine, bilirubin and INR) [2]. This evidence concerns the gene F2 and End Stage Liver Disease.