After the intervention, no differences between the groups were found in respect of body weight (p = 0.58), BMI (p = 0.16), neck circumference (p = 0.37), waist circumference (p = 0.14), abdominal circumference (p = 0.23), hip circumference (p = 0.82), body fat mass (p = 0.40), body lean mass (p = 0.98), glucose (p = 0.41), insulin (p = 0.83), HOMA-IR (p = 0.95), HOMA-AD (p = 0.55), adiponectin (p = 0.36), leptin (p = 0.74), adiponectin/leptin (p = 0.23) and ANP (p = 0.75). The gene discussed is INS; the disease is Alzheimer disease.