PIK3CA and breast carcinoma: Using the published high-depth transcriptomic data on PIK3CAWT/H1047R and PIK3CAH1047R/H1047R iPSCs [43], we next performed GSEA with the two gene set signatures used for PI3K signaling and stemness score calculations in the breast cancer setting (MSigDB “HALLMARK_PI3K_AKT_MTOR_SIGNALING” and PluriNet, respectively).