ABCB7 was also found to be critical for hematopoiesis as conditional deletion with Mx1-cre resulted in rapid bone marrow failure with pancytopenia (Pondarre et al., 2007), but the requirement of ABCB7 for the development of specific hematopoietic lineages was not examined. The gene discussed is ABCB7; the disease is Bone marrow hypocellularity.