We comprehensively probed into the roles of Solute carrier family 7 member 11 (SLC7A11), a ferroptosis regulatory gene in prognosis, immune microenvironment, biological metabolism, therapeutic correlation, and pro‐oncogenic abilities of renal cell carcinoma (RCC) through bioinformatic analyses and experimental validation. This evidence concerns the gene SLC7A11 and renal cell carcinoma.