For instance, lnc‐KCNQ1OT1 is able to inhibit inflammation through nuclear factor kappa B inhibitor alpha (IκBα) and regulating microRNA (miR)‐506‐3p,6, 8, 9 while lnc‐KCNQ1OT1 has the capacity to attenuate multiple organ dysfunction (such as cardiomyopathy, liver injury, and sepsis‐induced cardiac injury) via several approaches, including regulation of miR‐214‐3p, caspase‐1, miR‐122‐5p and carboxylesterase 2, as well as miR‐192‐5p and the X‐linked inhibitor of apoptosis protein (XIAP) axis.7, 10, 11. This evidence concerns the gene CES2 and injury.