CD4 and multiple sclerosis: GO analysis of the 5156 significantly differentially expressed genes betweenblood and CSF CD4+ cells in NID controls identified 61significant GO terms at FDR <5% (Supplementary Table 12).GO analysis of the 4263 significantly differentially expressed genes betweenblood and CSF CD4+ cells in multiple sclerosis identified 176significant GO terms at FDR <5% (Supplementary Table 13).The GO term ‘Movement of cell or subcellular component’ was themost significant term in both NID controls (fold enrichment 1.23, FDR 5 ×10−7) and multiple sclerosis (fold enrichment 1.32, FDR2.7 × 10−10).