To determine whether AUF1 plays a role in DICER1 regulation in MCC, we silenced AUF1 using two different siRNAs (siAUF1#1 and siAUF1#2) in MCPyV+ (WaGa and MKL-1) and MCPyV− (MCC26) cell lines and evaluated the effect on DICER1 protein expression. The gene discussed is HNRNPD; the disease is Merkel cell skin cancer.