Due to the importance of inflammation in the development and progression of AADs/AAAs, the present study aimed to utilize PFCs in combination with 1H/19F MRI to visualize inflammatory processes and the accumulation of monocytes and macrophages in the aortic vascular wall of angiotensin II (angII) treated apoE-deficient (apoE−/−) mice, a well-established mouse model known to result in a portion of animals in AAD and AAA (25, 26). The gene discussed is APOE; the disease is achalasia-alacrima syndrome.