And the AUC of IFI44 in differentiating active LN from inactive LN patients was 0.697, which was similar to clinical indicators such as anti-dsDNA (AUC = 0.600), C3 (AUC = 0.665), and C4 (AUC = 0.673) (Figure 5D; Supplementary Table 7). The gene discussed is C3; the disease is lobular neoplasia.