-↓ISG expression -↓Antiviral response -NC in viral RNA levels in the lung (more infectious virus in STAT2-/-) -↑Proinflammatory cytokines in the lung -↓Lung pathology and PMN cells infiltration (STAT2-/-) -Bronchopneumonia and peribronchiolar inflammation (IL28R-a-/-). The gene discussed is STAT2; the disease is bronchopneumonia.