TUG1 and cancer: Recent studies have been indicated that TUG1 is dysregulated in numerous human cancers and acts as an unfavorable predictor of survival for patients with cancer, such as renal cell carcinoma, ovarian cancer, bladder urothelial carcinoma, oral squamous cell carcinoma, esophageal squamous cell carcinoma, hepatocellular carcinoma, and intrahepatic cholangiocarcinoma (137, 138).