Meanwhile, MiR-1207-5p can target STAT6 to promote breast cancer growth (32), DNMT1 is a critical factor responsible for DNA methylation modification (22), VEGFA can trigger aberrant angiogenesis and induce immune evasion (23), and IGFBP5 is capable of regulating the insulin-like pathway (33). The gene discussed is IGFBP5; the disease is breast cancer.