STAT3 and neoplasm: For example, we found that Linc00152 can stimulate proliferation, epithelial to mesenchymal transition (EMT), migration and invasion (8); lncRNA GAS5 has a tumor suppressive role to induce cell cycle G1 arrest and inhibit malignant proliferation (9); and lncRNA PVT1 can activate STAT3 signaling pathway to trigger angiogenesis and vasculogenic mimicry, thereby promoting tumor growth in gastric cancer (10, 12).