P2RX4 and infection: By using viral miR-133b infection adult mouse spinal cord model, Thomas Theis, etc. observed reduction of RhoA, xylosyltransferase 1 (Xylt1), ephrin receptor A7 (Epha7), and purinergic receptor P2X ligand-gated ion channel 4 (P2RX4), that has been determined as a negative factor in neurite outgrowth [61].