TMX1 and breast carcinoma: TMX has cytostatic and cytotoxic properties in the MCF-7 breast cancer cell line, not only stopping proliferation and inducing apoptosis, but also inducing differentiation and reducing cholesterol synthesis (Kedjouar et al., 2004; Medina, Favre & Poirot, 2004); it also modulates immunity in patients with breast cancer (Robinson et al., 1993; Behjati & Frank, 2009).