Also, modification of the gene expressions of enzymes G6pc and Fbp1 (fructose‐bisphosphatase 1 gene), involved in glucose hepatic production in vivo, and also Pck1 (phosphoenolpyruvate carboxykinase 1 gene) was studied in two experimental animal models of impaired glucose metabolism (insulin resistance IR and STZ models), where, after γ‐conglutin treatment, G6pc (glucose‐6‐phosphatase gene) expression was decreased in the IR‐γ‐conglutin and STZCγ groups. This evidence concerns the gene G6PC1 and Insulin resistance.