Inversely, CDX2 is ectopically turned on outside the gut in precancerous intestine-type metaplasia and associated adenocarcinoma of foregut-derived organs including stomach and esophagus (Moskaluk et al., 2003), even though patients survival correlates with the CDX2 level in gastric cancers (Seno et al., 2002). This evidence concerns the gene CDX2 and adenocarcinoma.