The enrichment pathways of the KEGG pathway in MSMO1 high expression phenotypes included glycolytic gluconeogenesis, P53 signaling pathway, glutathione metabolism pathway, and the enrichment pathways in low expression phenotypes included systemic Lupus erythematosus, vascular smooth muscle contraction, cytokine receptor interaction, focal adhesion, chemokine signaling pathway, Leishmania infection pathway (Figure 9; Table 3). Here, TP53 is linked to systemic lupus erythematosus.