Subsequently, we sorted separate sets of CD4+ TEG011 cells that co-expressed either exogenous CD8αα (CD4+CD8α+) or CD8αβ (CD4+CD8αβ+) as well as TEG011 cells expressing only endogenous CD4 and CD8 as negative and positive controls for tumor recognition, respectively (Figure 1A). This evidence concerns the gene CD4 and neoplasm.