In contrast to MPO-ANCA GN, the strongest association between neutrophilic infiltrates and severe kidney injury reflected by rise of serum creatinine (r=0.6281, p=0.0008), eGFR loss (r=-0.5805, p=0.0023), and requirement of RRT (r=0.4369, p=0.0290) was observed in PR3-ANCA GN (Figure 7B). The gene discussed is MPO; the disease is ganglioneuroma.