SLC5A2 and hydrops fetalis: There are also many trials reported effects of different SGLT-2 inhibitors in HF patients, like canagliflozin (17), Dapagliflozin (9), sotagliflozin (10), luseogliflozin (12), while the others like ertugliflozin (18), ipragliflozin (19) and tofogliflozin (20) are mainly focusing on T2DM patients.