By comparing the different models of INF-γ + 874 T/A (rs2430561) genotype as a risk estimate with different variables of tumor in BC group, results revealed no association with ER, PR, metastasis or operation type (Supplement Tables, (ER) 5, (PR) 6, (Metastasis) 7 and (Operation Type) 8). The gene discussed is ESR1; the disease is neoplasm.