Interestingly, we observed significant enrichment of the gene sets of NF-κB and MAPK pathways in ALKBH5 high-expression cases from the cohorts of patients with MM (GSE26760 [34] and GSE19784 [35]) by GSEA (Figs. 8B; S8A, B), suggesting that ALKBH5 also positively regulated these pathways. Here, NFKB1 is linked to Miyoshi myopathy.