Other SNPs showing significant association with plasma follistatin include exm1435650 in the ZNF333 gene (p = 1.98E-11), exm831645 in ADAMTS14 (p = 5.50E-11), exm373967 in TEME44 (p = 2.05E-09) and exm646262 in CUX1 which have been shown to be genetic factors influencing elevated markers of death receptor-activated apoptosis associated with increased diabetes and cardiovascular disease risks34. This evidence concerns the gene ZNF333 and cardiovascular disorder.