Its expression is upregulated in many acute and chronic inflammatory diseases such as sepsis [19], passive cutaneous anaphylaxis and atopic dermatitis [9], Alzheimer’s disease [20, 21], dementia [22], schizophrenia [16, 23], diabetic nephropathy [24, 25], and cancer [15, 26, 27], suggesting that swiprosin-1 played a role in inflammation processes of many diseases. The gene discussed is EFHD2; the disease is atopic eczema.