SNORA42 silencing also led to a marked increase in the percentage of apoptotic cells (Fig. 2c), along with a reduction in the proliferative capacity of HCC cells, as indicated by the reduced absorbance in CCK8 assay (Fig. 2d), fewer and smaller colonies (Fig. 2e) and lower EdU incorporation (Fig. 2f), compared to the control cells. Here, SNORA80E is linked to hepatocellular carcinoma.