Consistent with the patient data, SNORA42 was upregulated in all HCC cell lines compared to the immortalized human liver cell line HL-7702 (Fig. 1b), and the expression levels were particularly high in the HCCLM9 (11.75 ± 0.8764, *p = 0.0002) and SK-Hep1 (5.000 ± 0.8238, *p = 0.0037) cells. The gene discussed is SNORA80E; the disease is hepatocellular carcinoma.