MYLK and cancer: NETs awakened cancer cells and there was concomitant remodeling of laminin, which was sequentially cleaved by two NET-associated proteases, NE and MMP-9, through the activity of integrin α3β1 and focal adhesion kinase/ERK/myosin light chain kinase/yes-associated protein (FAK/ERK/MLCK/YAP) signaling [97].