Moreover, TGFBR3L showed a relative high expression level in the triple PitNET containing a gonadotroph component, in one “null cell adenoma” that showed a gonadotroph mRNA profile, and in the PIT1 positive FSH-oma, all well consistent with gonadotroph expression of TGFBR3L. Interestingly, a relatively high expression level was also evident in one PIT1 and one TPIT tumor, both with high mRNA expression of gonadotroph markers, supporting an interplay between the pituitary cell lineages in PitNET development. The gene discussed is BRD2; the disease is neoplasm.