Interestingly, most of these genes have been implicated in general mechanisms of tumor biology, such as SERPINF1, reported as an inhibitor of angiogenesis and tumor suppressor [58], ASAP2, an EGFR pathway activator [15], or ELN and KRT8 related to the process of EMT [22, 52]. The gene discussed is SERPINF1; the disease is neoplasm.