COPS5 and ovarian neoplasm: DUBs belong to a subset of the protein family called cysteine proteases and are further classified into five families: ubiquitin-specific proteases (USPs), ovarian tumor proteases (OTUs), ubiquitin C-terminal hydrolases (UCHs), Machado-Joseph disease protein domain proteases (MJDs), and Jab1/Mov34/Mpr1 Pad1 N-terminal+ MPN+ (JAMM) motif proteases [13].