NOD2 and inflammatory bowel disease: Analysis of the promoters of the genes activated by the expression of these four IBD genes (Additional file 1: Table S6) found an enrichment of binding sites for STAT1::STAT2 and for members of the IRF family in three of these (IFIH1, SBNO2, and NFKB1) and of NFkB sites (REL and RELA) in two (NFKB1 and NOD2).