MYC and ovarian carcinoma: Data generated by The Cancer Genome Atlas [4] reported that the top three most common focal amplifications found in HGSOC patients encoded the genes MECOM, CCNE1 and MYC. The BRD4 gene represents the 4th most frequent somatic amplification in HGSOC [10], and its amplification is present in 18% of ovarian cancer patients [4, 10].