Here, the impact of a malaria episode on the expression of FcRL5 on the cell surface of naïve B cells (CD21+CD27−), classical MBCs (CD21+CD27+), activated MBCs (CD21−CD27+), and atypical MBCs (CD21−CD27−) was evaluated by flow cytometry (Fig. 2B, Additional file 1: Figs. S2–S4). This evidence concerns the gene CD27 and malaria.