similarly, in a subgroup within the Health Professionals Follow-up Study consisting of 18.225 men followed-up for 14 years, adiponectin was associated with a 42% lower risk of PAD per SD increase, with only a small attenuation after adjustment for HDL-C, LDL-C, CRP and cystatin C [40]. The gene discussed is ADIPOQ; the disease is peripheral arterial disease.