Lastly, the expression of ITGB1 was detected in gastric tumor tissues from clinical patient by immunohistochemistry, in which tumor tissues from high stage patients (n = 10, stage T3–T4) revealed elevated ITGB1 expression compared to the low stage group (n = 10, stage T1–T2) (Fig. 2K). Here, ITGB1 is linked to gastric neoplasm.