Subsequently, to further investigate the function of HK2 on regulating cell motility and tumor metastasis in human cervical cancer cells, exogenous HK2 was stably overexpressed by transfection of an HK2 recombinant plasmid in HeLa (HeLa-Vec and HeLa-HK2, Fig. 1A) and SiHa (SiHa-Vec and SiHa-HK2, Fig. 1C) cells. This evidence concerns the gene HK2 and neoplasm.