CLN5 and fibrodysplasia ossificans progressiva: Since BMPs control skeletal muscle differentiation from hiPSCs (Chal et al., 2016; Xi et al., 2017), we investigated if genetic activation of the BMP pathway via ACVR1R206H could alter the myogenic differentiation of hiPSCs (F1-1, F2-3, F3-2) derived from patients with FOP (Matsumoto et al., 2013).