Using immunoblotting, Dual-Luciferase reporter, and immunocytochemistry assays, Liu et al. (2018) found that miR-708-5p could be used as a new diagnostic and prognostic marker for NSCLC, the study showed that miR-708-5p directly inhibited the translation of DNMT3A, resulting in a significant decrease in genome-wide DNA methylation and upregulation of the tumor suppressor CDH1. Here, CDH1 is linked to non-small cell lung carcinoma.